In contrast to diluted CNS SLE CSF samples, anti-NR2A antibody induced a fast calcium transient (0.66 ± 0.10, n = 38) that peaked at 6 s, showed a slow component (0.46 ± 0.03) 3 min after and remained even after wash (Fig. 10c). The gene discussed is GRIN2A; the disease is systemic lupus erythematosus.