After stimulation with LPS, CD133+ CSCs isolated from four CSC samples derived from four fresh human surgical glioma tissues, pT1 to pT4, also demonstrated enhanced proliferation (Figure 3e; P < 0.01, compared to CD133+ CSCs without LPS stimulation), whereas PBMCs did not (Figure 3e). The gene discussed is PROM1; the disease is central nervous system cancer.