AR and posterior cortical atrophy: To explore whether that expression of CXCL13 is up-regulated by androgen, AR-positive human PCa cell lines LNCaP and CWR22Rv1 were respectively hormone-stripped for 3 days (cells cultured in CSS medium), and then treated with different doses of mibolerone (Mib), a synthetic potent anabolic androgen which is both high affinity and selectivity for AR.