HOXA-AS3 and glioblastoma: Since gain of chromosome 7 is one of most common genetic alteration in glioblastoma [22], the increased expression of HOXA-AS3 might be attributed to the amplification of chromosome 7, or the regulation of transcriptional activation and mRNA stability, and the amplification of chromosome 7 may be the main reason of upregulation of HOXA-AS3 which needs further study.