COL1A1 and pulmonary arterial hypertension: In addition, we identified promoters involved in inflammatory process known to have a major role in PAH including ZAP70 (Syk-Related Tyrosine Kinase), STAT5A (Signal Transducer and Activator of Transcription 5A), COL1A1 (Alpha-1 Type I Collagen) and TNFSF4 (Tumor Necrosis Factor Superfamily Member 4) (Figure 1B, Tables 2 and 3).