TUSC3 and non-small cell lung carcinoma: We determined that the autophagy ratio, as well as Beclin, p-β-catenin, and LC3 II/LC I expression were increased in the TUSC3 group, but decreased in the TUSC3 siRNA group compared to the blank and vector control groups, suggesting that overexpression of TUSC3 accelerates autophagy in NSCLC cells through activation of the Wnt/β-catenin signaling pathway.