All mice from Tg2; Hi-Myc and Hi-Myc groups (∼3 months) developed multiple PINs and adenocarcinomas in their prostate glands and H&E staining indicated that the histological features of AP and DLP (dorsal and lateral prostate) lobes in the two groups of mice were overall similar (Figure 5D). Here, MYC is linked to adenocarcinoma.