GABBR1 and nasopharyngeal carcinoma: Secondly, the SNP-11 variation (GABBR1, rs29232, G>A) might have a protective role in the development of NPC, because the risk of the SNP-11 mutant genotype was lower than that of the wild-type (OR = 0.204, 95% CI: 0.079-0.528).