On multivariate analysis, total RT dose of BED 55 Gy or greater was significantly associated with LPFS (P=0.04, HR 3.18, 95% confidence interval [CI] 1.07-9.49) and liver cirrhosis (P=0.03, HR 3.26, 95% CI 1.12-9.47), while pretreatment AFP >200 ng/ml (P=0.12, HR 2.12, 95% CI 1.20-3.75) was significantly associated with PFS (Table 4). Here, AFP is linked to cirrhosis of liver.