FAP and Miyoshi myopathy: The abnormal p-AKT level was distinctly decreased to 0.153 ± 0.012 (Figure 6A, P = 0.017), Owing to the inappropriate PI3K activation in MM-BMSCs co-cultured CD4+ T-cells, we can conclude that MM-BMSCs might suppress CD4+ T-cell function through the FAPα/PI3K pathway.