CD4 and Miyoshi myopathy: A reduced inhibition of T lymphocyte proliferation, a lower ability to silence mitogen-stimulated T-cells in G0/G1 phase, a reduced inhibition of T-cell activation, a reduced rate of T-cell apoptosis and increased Th17/Treg ratio have been observed during the co-culture of CD4+T-cells with MM-BMSCs compared to the co-cultures with healthy donor (HD) BMSCs [9].