Recently, several studies indicated that PODXL might be a predictor of prognosis in various cancers, such as colorectal cancer (CRC) [9–12], pancreatic cancer (PC) [13–15], glioma [16], esophageal and gastric adenocarcinoma (EGAC) [17, 18], urothelial bladder cancer (UBC) [19], breast cancer (BC) [20] and so on. Here, PODXL is linked to central nervous system cancer.