The small cohort of stage 3 neuroblastomas in our prior analysis showed αvβ3 expression on 87% of microvessels in the MYCN-amplified neuroblastomas (high risk group; n = 3) but only on 20% of microvessels in the non-MYCN amplified tumors (intermediate risk group; n = 2), suggesting possible correlation between microvascular αvβ3 expression and risk group in the stage 3 neuroblastoma tumors. Here, MYCN is linked to neuroblastoma.