Moreover, in an in vitro experiment, Kaur et al (2015) reported a high frequency of homotypic cell fusion in a glioblastoma cell line resulting in a hybrid subpopulation demonstrating decreased radiation-induced stress, increased senescence-associated secretory proteins (SASPs), and upregulated anti-apoptotic genes like BIRC3 and Bcl-xL [55]. This evidence concerns the gene BCL2L1 and glioblastoma.