NTN1 and familial pancreatic carcinoma: In tumors, netrin-1 acted as an oncogene that was overexpressed in several cancers, such as colorectal cancer [7, 8], hepatic cancer [5], neuroblastoma [9], medulloblastoma [10], pancreatic cancer [11, 12], breast cancer [2], prostate cancer [13], and non-small cell lung cancer [14].