Therefore, in this work we used translational PET imaging to demonstrate the in vivo targeting of Pep-1L, a peptide reported to target IL13RA2 [7], an attractive tumor-associated biomarker that we and others have demonstrated to be present on a number of deadly malignancies, including GBM and melanoma [13, 41, 42]. The gene discussed is IL13RA2; the disease is neoplasm.