CDKN1B and anaplastic large cell lymphoma: In anaplastic large cell lymphoma (ALCL), an aggressive human T cell lymphoma, miR-106a~363 is highly expressed (especially miR-106a and miR-20b), whereas the same tumor type typically exhibits a PI3K-dependent loss of the Cdk inhibitor protein p27Kip1 (Cdkn1b) [5–7].