For example, previous study showed that the haplotype of IL1B, IL1RN, IL1R1, and IL1R2 increased the risk of venous thrombosis [11], and IL1/IL1Ra, CTLA-4 and Apo1/Fas genes polymorphisms associate with IgA nephropathy [12]. This evidence concerns the gene IL1B and IgA glomerulonephritis.