CLMB and familial pancreatic carcinoma: To investigate endogenous C16orf74 expression at the protein level, we generated an anti-C16orf74 polyclonal antibody which can recognize V1 and V3 proteins, but not V2 protein, and performed Western blot analysis using extracts from pancreatic cancer cell lines as well as COS7 cells in which C16orf74-V1 protein expression vector was exogenously introduced.