To understand the effects of AURKA inhibition, in the context of HR-proficiency and HR-deficiency, we employed a large panel of established ovarian carcinoma cell lines, including PEO1, SKOV3ip2, PEO4, OVCA429, MDAH, A2780, OVCAR5 and OVCAR10. The gene discussed is AURKA; the disease is ovarian carcinoma.