PDK1 and Stroke: Although there was a trend to increase in both vehicle and GSK360A groups the post-stroke HO 1, and stromal cell-derived factor 1 and EPO in both hemispheres (not significant; data not shown), there were also no significant brain changes in the mRNA expression for PDK-1 or EGL nine homolog 2 in either brain hemisphere following stroke for either group (not significant; data not shown).