DNAJB1 and amyloidosis: A molecular understanding of the amyloid fibrils’ stability towards fragmentation, as well as how fibril fragmentation is catalyzed in the cell by chaperones such as Hsp104, Hsp70 and Hsp40, will lead us to a better understanding, and suggest diagnostics and therapeutics to combat amyloid transmission, amyloid disease progression and prion infectivity.