HN protein can also promote fusion activity via its interaction with the F protein and act as an NA by removing sialic acid from progeny virus particles to prevent viral self-aggregation, aiding virus infection (Mirza et al., 1994; Huang et al., 2004; Melanson and Iorio, 2004; Heiden et al., 2014; Liu B. et al., 2015; Jin et al., 2016). The gene discussed is XK; the disease is viral infectious disease.