CD274 and melanoma: BMS-936559, Avelumab, MEDI4736, and, Atezolizumab are the anti-PD-L1 antibodies that are being studied for various cancers and tumors including melanoma, multiple myeloma, leukemia, lymphoma, glioblastoma as well as gastric, renal cell, bladder, colorectal, hepatocellular, cutaneous, breast and NSCLC (Non-Small Cell Lung Cancer) cancers, (CRC), castration-resistant prostate cancer (CRPC), renal cell carcinoma (RCC), head and neck squamous cell cancer (HNSCC).