In addition, interrogation of several chemokines and cytokines known to be modulated in our tumor model23 revealed an increase in trafficking chemokines CXCL9 and CXCL10, and a decrease in the immunosuppressive cytokine VEGFA, consistent with studies showing these changes enhance CD8 T-cell function5, 24–26. The gene discussed is VEGFA; the disease is neoplasm.