Here, we found that WP_031391632.1 was again significantly upregulated in Plin2-null mice relative to WT under a LF diet, but was significantly downregulated in Plin2-null mice under a HF diet (RPKM = 124.9, 1.7, 0.4, and 47.9 for Plin2-LF, Plin2-HF, WT-LF, and WT-HF, respectively). This evidence concerns the gene PLIN2 and hydrops fetalis.