Under a LF diet, CLS_10500 exhibited almost 90-fold higher expression in Plin2 mice relative to WT (95.6 ± 112.6 vs. 1.10 ± 1.32 RPKM for Plin2 vs. WT; Additional file 4: Table S3), but was diminished over 200-fold (1.49 ± 1.96 vs. 345.2 ± 685.7 RPKM for Plin2 vs. WT) under a HF-diet. This evidence concerns the gene PLIN2 and hydrops fetalis.