However, this conclusion is difficult to reconcile with our finding that the genes and pathways modulated by HF vs. LF diet differed between Plin2 and WT groups (Fig. 3, noting the contrast of Diet-Plin2 with Diet-WT), as well as between HF-fed Plin2 and WT groups (Fig. 3, Geno-HF comparison). The gene discussed is PLIN2; the disease is hydrops fetalis.