Hyperlipidemia is often accompanied with complex dyslipidemia, such as elevated very low-density lipoprotein cholesterol (VLDL-C) and LDL-C levels and low high-density lipoprotein cholesterol (HDL-C) levels, which are associated with serum apolipoprotein M (apoM) [2]. The gene discussed is APOM; the disease is hyperlipidemia.