Narita et al. previously reported that GLI2 expression correlated with a more advanced PCa phenotype [17], whilst Kim et al. demonstrate correlations between Hh signaling molecules (GLI1, SHH, SMO, PTCH1) and GS score here, however in this latter study GLI2 expression was not assessed [18]. The gene discussed is GLI1; the disease is posterior cortical atrophy.