However, the proof that DNA aneuploidy can predict the progression of given OPMD in a clinical setting is still missing and the same applies for some molecular markers, such as p53 (TP53), Cyclin D1, and podoplanin (PDPN), HIF-1alpha, E-cadherin, and p63, which were also investigated [14, 15]. The gene discussed is PDPN; the disease is oculopharyngeal muscular dystrophy.