GFER and steatosis: Therefore we analyzed ALR mRNA expression in human liver samples and found significantly reduced ALR mRNA levels in patients with steatosis (0.83 ± 0.26, n = 27) and NASH (0.64 ± 0.22, n = 29) compared to normal liver tissue (1.31 ± 0.48, n = 17) (Fig 7A).