PVT1 and acute myeloid leukemia: This is consistent with the pan-progenitor expression of this lncRNA in contrast with the AML-specific nature of Pvt1 and Lilam. Further studies will be required to determine the breadth of lncRNA roles in the hematopoietic system, though this gives us reason to believe that the normal setting, just like AML, will be heavily dependent on these non-coding transcripts.