PVT1 and leukemia: Gene Set Enrichment Analysis (GSEA) showed an enrichment for Macrophage Differentiation genes (Ingenuity Pathway Analysis list) upon knockdown of lnc_071255 (already annotated as Pvt1), lnc_104449, or lnc_177417, while leukemia stem cell signatures (Krivtsov et al., 2006) showed enrichment in the control knockdown (Figure 5B).