Potential role of hepcidin in iron deficiency among obese population was proved by finding high level of hepcidin in cases with severe obesity and positive correlation between adipose tissue expression of hepcidin and BMI.1In addition, we demonstrated BMI as an independent prognostic factor for inflammatory markers, CRP and hepcidin, using multivariate multiple regression models. The gene discussed is CRP; the disease is obesity due to melanocortin 4 receptor deficiency.