TFRC and obesity due to melanocortin 4 receptor deficiency: These studies reported lower levels of serum iron in obese adolescents in comparison to normal weight peers.5 During past years, some studies investigated the correlation between iron deficiency and obesity.10, 11 After reports of increasing iron deficiency prevalence among obese and overweight population, new studies have recently started to focus on this issue.12Lecube et al.12 reported that obese menopause women have higher levels of sTfR compared to non-obese control subjects.