D35 ID8-Muc16ecto PD-L1−/− tumor-bearing mice treated with 4H1128ζ-IL12 T cells did not exhibit significant differences in median overall survival compared to WT ID8-Muc16ecto treated with 4H1128ζ-IL12 T cells (N.S, solid red line vs. dotted red line). This evidence concerns the gene CD274 and neoplasm.