In vivo, treatment of D35 ID8-Muc16ecto PD-L1−/− tumor-bearing mice with 4H1128ζ T cells rescued the attenuated efficacy seen with mice inoculated with WT ID8-Muc16ecto at the same time point (*p < 0.001, solid black line vs. dotted black line) (Fig. 6e). Here, CD274 is linked to neoplasm.