We also infected WT mice and mice lacking the fpr1 gene and showed significantly higher survival rate, lower parasitemia, less body weight loss, and reduced splenic cell death in the FPR1-deficient mice than WT mice (Fig. 7g-j), suggesting that this specific necroptosis pathway mediated through interaction between annexin A1 and FPR1 may play a role in the N67C-induced cell death. Here, FPR1 is linked to parasitic infectious disease.