The top 18 of the 20 most active KEGG pathways involved were also consistent: pathways in cancer, PI3K-Akt signaling pathway, focal adhesion, proteoglycans in cancer, HTLV−I infection, MAPK signaling pathway, rap1 signaling pathway, cAMP signaling pathway, regulation of actin cytoskeleton, calcium signaling pathway, endocytosis, Huntington’s disease, cGMP−PKG signaling pathway, oxytocin signaling pathway, Alzheimer’s disease, ras signaling pathway, viral carcinogenesis, and platelet activation pathways. The gene discussed is AKT1; the disease is Huntington disease.