Clinical factors associated (p < 0.05) with an increased risk of malignancy included cyst size greater >3 cm (OR (95% CI) = 2.60 (0.76–8.86, p = 0.127), main duct involvement (OR (95% CI) = 11.00 (2.26–53.63, p = 0.003), and serum albumin levels (OR (95% CI) = 0.35 (0.11–1.15, p = 0.083). This evidence concerns the gene ALB and cyst.