DLG4 and autism spectrum disorder: Preterm infants have an increased risk of developing autism spectrum disorders (ASD) and other neuropsychiatric disorders, and DLG4 has been consistently associated with neuropsychiatric diseases including ASD and schizophrenia30, 63 (Supplementary Data 11), while mice with Dlg4 deletion (Dlg4−/−) exhibit increased repetitive behaviour, abnormal communication and social behaviour31.