Both organisms also proved useful in the study of non-neurologic phenotypes, such as the role of ZSWIM6 in acromelic frontonasal dysostosis (MIM# 603671) (Smith et al. 2014), CAV1, and neonatal lipodystrophy (Garg et al. 2015), WDPCP (MIM# 217085 and 615992) and INTU in ciliopathy syndromes (Toriyama et al. 2016), and FOXE in thoracic aortic aneurysms and dissections (Kuang et al. 2016). The gene discussed is CAV1; the disease is Acromelic frontonasal dysplasia.