Both organisms also proved useful in the study of non-neurologic phenotypes, such as the role of ZSWIM6 in acromelic frontonasal dysostosis (MIM# 603671) (Smith et al. 2014), CAV1, and neonatal lipodystrophy (Garg et al. 2015), WDPCP (MIM# 217085 and 615992) and INTU in ciliopathy syndromes (Toriyama et al. 2016), and FOXE in thoracic aortic aneurysms and dissections (Kuang et al. 2016). This evidence concerns the gene INTU and Acromelic frontonasal dysplasia.