In the current article, several dysregulated lncRNAs involved in the regulation of radioresistance, metastasis and cancer stem cell properties, such as ANRIL, TUG1, LOC285194, LncRNA-ROR, MALAT1, NEAT1, HOTAIR, POU6F2-AS2, GAS5, HIF2PUT, H19, TALNEC2, HOXA11-AS, Linc00617, HULC, and UCA1, have been found to be associated with the outcomes of radiotherapy and act as valuable prognostic biomarkers (Table 1 and Figure 1B,C). The gene discussed is CDKN2B-AS1; the disease is cancer.