2012). As described earlier, AOM induces oxidative stress by depleting the level of GSH; in the present study treatment with MEMCL restores the GSH level indicating the protective effect of MEMCL. Besides GSH, AOM also depleted the level of CAT and SOD, which was reverse and restore back towards normal value by MEMCL. The administration of AOM also induced a marked increase in MDA level, which was reduced by MEMCL indicating the cytoprotective action of the extract. The gene discussed is SOD1; the disease is infectious otitis media.