A genetic study found that HLA-DRB1*11:01 is associated with a higher risk of anti-HMGCR IMNM in both white American and African American adult populations, whereas HLA-DRB1*07:01 seem to be associated with a risk of anti-HMGCR myositis in small series of children (86, 87). This evidence concerns the gene HLA-DRB1 and myositis disease.