NR1H3 and coronary artery disorder: LXRα gene expression was significantly upregulated in DM+CAD− (ΔCT = 2.77 ± 1.36; fold change = 4.51 ± 0.20 P = 0.006), DM+CAD+ (ΔCT = 3.27 ± 1.79; fold change = 3.19 ± 0.42; P = 0.008), and DM−CAD+ (ΔCT = 2.15 ± 1.16; fold change = 6.93 ± 0.70; P < 0.001) compared to the HS (ΔCT = 4.94 ± 2.14), with a significant difference between the two CAD groups (P = 0.03) (Figure 3B).