Molecular analysis showed that SOD2 mRNA was downregulated in DM+CAD− (ΔCT = 5.70 ± 3.28; fold change = 0.10 ± 0.03; P = 0.001), DM+CAD+ (ΔCT = 4.57 ± 3.56; fold change = 0.22 ± 0.08; P = 0.03), and DM−CAD+ (ΔCT = 5.75 ± 3.04; fold change = 0.10 ± 0.05; P = 0.001) compared to HS (ΔCT = 2.36 ± 2.61), with no statistically significant difference between the two CAD groups (with and without DM) (Figure 3A). Here, SOD2 is linked to diabetes mellitus.