Silencing of NFIX reduced the expression of its regulated genes IL6ST, TIMP1 and ITGB1. Necula et al. (2012) showed that increased levels of IL6ST in tissues (>758 pg/ml) and plasma (>38.21 pg/ml) are associated with shorter survival in gastric adenocarcinoma. This evidence concerns the gene IL6ST and gastric adenocarcinoma.