The copy number status of TET2 (on 4q24), IRF1 (5q31.1), NPM1 (5q35.1), LAMB4 (7q31.1), EZH2 (7q36.1), ETV6 (12p13.2), TP53 (17p13.1), NF1 (17q11.2), ASXL1 (20q11.21), RUNX1 (21q22.12), and STAG2 (Xq25) have been investigated in a large cohort of MDS patients18. This evidence concerns the gene NPM1 and myelodysplastic syndrome.