As proof of principle examples, TP63, a marker of normal basal cells of the prostate gland was upregulated in benign microdissected epithelial samples compared to invasive cancer, while AMACR and ERG were all upregulated in the tumor microdissected epithelial samples compared to benign epithelium and, to a lesser extent, PIN (Supplementary Fig. 2). The gene discussed is AMACR; the disease is neoplasm.