NFKB1 and myocardial infarction: They hypothesized that as NF-κB is the key factor in regulating expression of different genes involved in the production of pro-inflammatory cytokines including IL-6 and IL-8 and expression of adhesion molecules such as ICAM, VCAM and epithelial leukocyte adhesion molecule (ELAM) all of which are involved in the formation of ischemia-reperfusion myocardial injury, suppressing its activity may result in prevention from myocardial infarction.