For example, soybean mosaic virus (SMV) strain G7 infection induced the overexpressed AGO1 mRNA to trigger the AGO1 siRNA-mediated AGO1 mRNA degradation pathway, resulting in the reduced AGO1 level, which requires SGS3, RDR6 andSDE5 as well as DCL4/2 [43]. This evidence concerns the gene AGO1 and infection.