ABCG1 and diabetes mellitus: However, genotyping of two functional ABCG1 SNPs (rs1378577, −134 T > G and rs1893590, −204 A > C in the promoter region) in 1320 French morbidly obese patients (BMI > 40 kg/m2) revealed that those two SNPs were associated with BMI after adjustment for diabetes and HOMA-IR [75].