Finally, the association of two functional ABCG1 SNPs (rs1378577, T > G and rs571137919, G > A) with the risk of ischemic stroke in a case-control study including 389 ischemic stroke patients and 380 healthy subjects in the Chinese Han population provided additional mechanistic insights about the deleterious effect of ABCG1 [98]. Here, ABCG1 is linked to ischemic stroke.