CYP1A1 is an important phase I enzyme andplays a key role in the metabolism of lipophilic xenobiotics.The enzyme is vitally expressed in malereproductive organs and its polymorphisms maybe a determinant of individual susceptibility to infertility.Metabolic activation or inactivation of xenobioticsis catalyzed by hemethilate enzymes likeCYP1A1, which catalyzes PAHs in the first stepof metabolism. Here, CYP1A1 is linked to Infertility.