SHBG and spindle cell hemangioma: High levels of total (T) and free testosterone (fT), LH, PRL, fasting and postprandial insulin, glycated hemoglobin (HbA1C), homeostasis model assessment of insulin resistance index (HOMA-IR), serum lipoprotein (a), triglyceride, total cholesterol (TC), unfavorable low-density lipoprotein (LDL) and high-density lipoprotein (HDL) and low levels of SHBG (8, 11), are independent risk factors for metabolic syndrome or myocardial infarction frequently described in SCH (11–13).