As well, in mice with myocardial infarction, relaxin treatment after myocardial infarction for 14 days also reduces AF through the decrease on fibrosis and hypertrophy, the increase in conduction velocity, and, moreover, the decrease of the pro-inflammatory cytokine IL-1β expression (Beiert et al., 2017). Here, IL1B is linked to myocardial infarction.